Document Detail

Heart rate recovery after exercise in adults with the Down syndrome.
MedLine Citation:
PMID:  20451697     Owner:  NLM     Status:  MEDLINE    
The main purpose of this study was to evaluate heart rate recovery (HRR) in patients with the Down syndrome (DS) after peak dynamic exercise and compare their responses to those of nondisabled subjects of similar age, gender, and body mass index. Eighteen participants with the DS (14 men, 4 women; mean age 33.6 +/- 7.6 years) and 18 nondisabled controls (14 men, 4 women; mean age 33.8 +/- 8.5 years) performed peak treadmill tests with metabolic and heart rate measurements. Compared to controls, subjects with the DS presented lower peak values of heart rate, oxygen uptake, and minute ventilation (p <0.05). In contrast, the 2 groups attained similar respiratory exchange ratio values at peak exercise. Even after controlling for the effects of reduced peak heart rate and body mass index, participants with the DS showed slower HRR than controls at 1 minute (DS: 25.3 +/- 7.2 beats/min; controls: 34.1 +/- 12.1 beats/min) and 2 minutes (DS: 36.3 +/- 5.8 beats/min; controls: 53.6 +/- 14.1 beats/min) of recovery (p <0.05). In conclusion, adults with the DS had reduced HRR (at 1 and 2 minutes of recovery) compared to nondisabled controls, and this was independent of their lower chronotropic response to peak exercise. Additionally, despite showing attenuated HRR from peak exercise, adults with the DS did not present increased cardiovascular risk by general diagnostic criteria (HRR >12 and 22 beats/min, respectively).
Goncalo V Mendonca; Fernando D Pereira
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-03-30
Journal Detail:
Title:  The American journal of cardiology     Volume:  105     ISSN:  1879-1913     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-10     Completed Date:  2010-06-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1470-3     Citation Subset:  AIM; IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Center of Human Performance, Faculty of Human Kinetics, Technical University of Lisbon, Lisbon, Portugal.
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MeSH Terms
Body Mass Index
Case-Control Studies
Down Syndrome / diagnosis,  rehabilitation*
Exercise Test / methods*
Exercise Tolerance / physiology
Heart Rate*
Middle Aged
Oxygen Consumption / physiology
Physical Exertion / physiology*
Recovery of Function
Reference Values
Time Factors
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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