Document Detail

Heart rate control with single administration of a long-acting β-blocker at bedtime before coronary computed tomography angiography.
MedLine Citation:
PMID:  25113950     Owner:  NLM     Status:  Publisher    
BACKGROUND: Beta-blockers are used to control the heart rate prior to coronary computed tomography (CT) angiography. However, in-hospital administration is time-consuming, and it is hard to decrease the heart rate to <60 beats per minute (bpm) when the initial heart rate is increased. In this study, we examined whether the single administration of long-acting β-blocker at bedtime before angiography is effective for achieving the target heart rate.
METHODS AND RESULTS: A total of 314 consecutive patients with a resting heart rate >60bpm who underwent coronary CT angiography were retrospectively collected. Either bisoprolol or atenolol was orally administered the night before to 166 patients (beta group), and no additional medication was administered to the other 148 patients (control group). When the heart rate was >60bpm on arrival, a β-blocker or verapamil was orally administered at the discretion of the physician. Although the baseline heart rate was not significantly different between the groups, the β-blocker treatment the night before significantly reduced the heart rate compared to control group upon arrival at the hospital and at the time of angiography. The rate of achievement of a heart rate ≤60bpm on arrival at the hospital was significantly higher in the beta group, and even after the additional treatment.
CONCLUSIONS: Bedtime administration of a long-acting β-blocker the night before coronary CT angiography is an effective option to achieve the target heart rate at the time of examination.
Kenji Sadamatsu; Sachiko Koide; Kayoko Nakano; Keiki Yoshida
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-8
Journal Detail:
Title:  Journal of cardiology     Volume:  -     ISSN:  1876-4738     ISO Abbreviation:  J Cardiol     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier Ltd.
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