Document Detail

Heart rate and blood pressure variability in orthostatic syncope.
MedLine Citation:
PMID:  8813829     Owner:  NLM     Status:  MEDLINE    
The pathogenetic role of autonomic nervous system in the neurally mediated orthostatic vasodepressive syncope is unclear. upright tilt was used to assess the characteristics of autonomic tone during orthostatic stress. We studied 18 patients (mean age 26 +/- 5 years) suffering from vasodepressive orthostatic syncope and with positive response to a 30-minute 60 degrees upright tilt and a comparable control group with a negative response to the upright tilt test. Blood pressure and heart rate (RR Interval) were measured beat-by-beat; ECG, systolic (SAP) and diastolic arterial pressure (DAP) and respiration trace were recorded for spectral analysis. The most important result of the work is a different pattern of the parameters evaluated, between fainters and controls, in the last period of tilt test, just before the syncope, and in the fainters group between the first (at the beginning) and the last period (just before syncope) of tilting. Baseline heart rate, arterial pressure and spectral indices were similar and increased with tilting in both groups (Low Frequency: LF; High Frequency: HF; LF/HF ratio). Just before the syncope, we observed in fainters group a decrease of heart rate, blood pressure, LF-RR, LF-DAP, LF-SAP, LF/HF -RR, and an increase of HF-RR and of total power where compared to in the same subjects in the first period of tilt and in front of controls in the same period of tilt. The novel aspect of the work, regarding the autonomic control of heart rate and arterial pressure, expressed by spectral fluctuations and by haemodinamic parameters, is consistent with a reduced sympathetic reserve in the immediate pre-syncopal period.
A Lagi; M Cipriani; A M Buccheri; C Tamburini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical science (London, England : 1979)     Volume:  91 Suppl     ISSN:  0143-5221     ISO Abbreviation:  Clin. Sci.     Publication Date:  1996  
Date Detail:
Created Date:  1996-10-21     Completed Date:  1996-10-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7905731     Medline TA:  Clin Sci (Lond)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  62-4     Citation Subset:  IM    
Department of Internal Medicine, Santa Maria Nuova Hospital, Firenze, Italia.
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MeSH Terms
Autonomic Nervous System / physiopathology*
Blood Pressure / physiology*
Heart Rate / physiology*
Signal Processing, Computer-Assisted
Syncope / physiopathology*
Tilt-Table Test
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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