Document Detail

Heart rate behavior during an exercise stress test in obese patients.
MedLine Citation:
PMID:  18804987     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIMS: Heart rate (HR) response to exercise has not been fully described in the obese. We wanted to study the differences between obese and non-obese patients in HR behavior during an exercise stress test and to determine whether these differences influence exercise capacity. METHODS AND RESULTS: We studied 554 patients (318 females) who underwent a treadmill exercise test. All subjects were in sinus rhythm. Patients with ischemic heart disease, with reduced ejection fraction and patients taking drugs that interfere with HR were excluded. The population included 231 patients with BMI<30 kg/m(2) (group 1), 212 patients who were unfit and obese (group 2) and 111 patients who were trained obese (group 3). Resting HR was similar in the various groups. Peak HR, HR recovery and chronotropic index were lower in obese subjects, regardless of their fitness level. Multivariate analysis showed that HR related variables were associated with age, BMI, height, hypertension and various pharmacologic treatments, while exercise capacity was strongly dependent on HR behavior, as well as on sex, age, BMI and diabetes. CONCLUSION: Obese subjects have a marked impairment of HR behavior during exercise and in the recovery period, and the blunted increase in HR is the most important factor that influences exercise capacity.
L A Gondoni; A M Titon; F Nibbio; G Augello; G Caetani; A Liuzzi
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Publication Detail:
Type:  Journal Article     Date:  2008-09-19
Journal Detail:
Title:  Nutrition, metabolism, and cardiovascular diseases : NMCD     Volume:  19     ISSN:  1590-3729     ISO Abbreviation:  Nutr Metab Cardiovasc Dis     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-03-16     Completed Date:  2009-06-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111474     Medline TA:  Nutr Metab Cardiovasc Dis     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  170-6     Citation Subset:  IM    
Unit of Cardiac Rehabilitation, Ospedale San Giuseppe, IRCCS, Istituto Auxologico Italiano, Via Cadorna, 90, 28824 Piancavallo di Oggebbio, Verbania, Italy.
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MeSH Terms
Age Factors
Body Height
Body Mass Index
Diabetes Complications
Echocardiography, Stress
Exercise Test*
Heart Rate*
Hypertension / complications
Middle Aged
Obesity / complications,  physiopathology*
Physical Endurance
Physical Fitness

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