| Heart rate-based protocols for exercise challenge testing do not ensure sufficient exercise intensity for inducing exercise-induced bronchial obstruction. | |
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MedLine Citation:
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PMID: 18308878 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine if a heart rate-based protocol for bronchial provocation testing ensures sufficient exercise intensity for inducing exercise-induced bronchial obstruction. PARTICIPANTS: 100 clinically healthy non-asthmatic sports students. DESIGN: Subjects underwent an exercise challenge test (ECT) on a treadmill ergometer for bronchial provocation according to the guidelines of the American Thoracic Society (ATS). Heart rate (HR), forced expiratory volume in 1 second (FEV(1)), pH (pH) and lactate concentration were measured before and after exercise. RESULTS: After exercise in 56% of the examined subjects lactate concentrations were < 6 mmol/l. A highly significant decrease in FEV(1) (mean -4.41 (SD 1.5%)) was found at concentrations of > 6 mmol/l, whereas at concentrations < 6.48 mmol/l, no participant showed an impairment of lung function (FEV(1) values < or = 90%). In five subjects, a bronchial obstruction was found, as shown by decreases in FEV(1) of -10 to -47% after exercise. The lactate concentrations in these individuals were between 6.48 and 11.7 mmol/l, indicating a predominantly anaerobic metabolic response to exercise. CONCLUSION: These results show that the ATS standard protocol, using a heart rate formula for assessing the exercise intensity, is not sufficient to cause predominantly anaerobic lactate metabolism and hence exercise-induced hyperventilation. Therefore, a potential bronchial obstruction could not be induced in 56% of the subjects. For a sensitive study design, exercise intensities demanding anaerobic lactate metabolism should always be ensured. A more precise protocol is required. |
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Authors:
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C Tr??mper; S M??ueler; C Vobejda; E Zimmermann |
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Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2008-02-28 |
Journal Detail:
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Title: British journal of sports medicine Volume: 43 ISSN: 1473-0480 ISO Abbreviation: Br J Sports Med Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-08 Completed Date: 2010-01-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0432520 Medline TA: Br J Sports Med Country: England |
Other Details:
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Languages: eng Pagination: 429-31 Citation Subset: IM |
Affiliation:
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Department of Psychology and Sports Science, University of Bielefeld, Universit??tsstr. 25, Bielefeld 33615, Germany. christian.truemper@uni-bielefeld.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Airway Obstruction / etiology*, physiopathology Bronchial Diseases / etiology*, physiopathology Bronchial Provocation Tests Clinical Protocols Exercise / physiology* Exercise Test / methods*, standards Female Forced Expiratory Volume Heart Rate / physiology* Humans Lactates / metabolism Male Sensitivity and Specificity Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Lactates |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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