Document Detail


Heart failure in septic shock: effects of inotropic support.
MedLine Citation:
PMID:  2403514     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Many animal studies have attempted to simulate the circulatory responses to Gram-negative septicemia (iv infusion of live bacteria, fecal inoculation into body cavities, and administration of purified endotoxins by various routes), but the contribution of the heart to the adverse hemodynamic derangements and thus to the pathogenesis of shock is difficult to determine because of peripheral vascular events that influence cardiac performance. When blood pools in the periphery, venous return decreases and cardiac output can decrease without a primary myocardial defect being present. However, early heart dysfunction has been recognized in sepsis. Hemodynamic monitoring has not reduced overall mortality, but it has been helpful in guiding fluid administration and evaluating response to vasopressor therapy.
Authors:
B Schremmer; J F Dhainaut
Related Documents :
12867304 - Biphasic and monophasic shocks for transthoracic defibrillation: a meta analysis of ran...
16942824 - Increasing first responder cpr during resuscitation of out-of-hospital cardiac arrest u...
8606274 - Early discharge in the thrombolytic era: an analysis of criteria for uncomplicated infa...
10488794 - Dynamic left ventricular outflow tract obstruction in acute coronary syndromes: an impo...
19098114 - N-acetyl-seryl-aspartyl-lysyl-proline prevents cardiac remodeling and dysfunction induc...
24189504 - Comparison of long-term outcome after percutaneous coronary intervention for stent thro...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical care medicine     Volume:  18     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-02-06     Completed Date:  1990-02-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S49-55     Citation Subset:  AIM; IM    
Affiliation:
Service de Réanimation Polyvalente, Cochin Port-Royal University Hospital, Paris, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cardiac Output
Combined Modality Therapy
Dogs
Heart / radionuclide imaging
Heart Failure / etiology,  physiopathology*
Hemodynamics*
Humans
Pulmonary Wedge Pressure
Rats
Shock, Septic / complications,  physiopathology*,  therapy
Stroke Volume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Practical application of oxygen transport principles.
Next Document:  Hemodynamic management in pulmonary embolism and acute hypoxemic respiratory failure.