Document Detail

Heart failure in experimental refractory shock.
MedLine Citation:
PMID:  791649     Owner:  NLM     Status:  MEDLINE    
Severe haemorrhagic shock was studied in a series of animal experiments. Reduction in myocardial oxygen and substrate utilisation in association with cardiac failure was demonstrated when the duration of shock was prolonged. The probable aetiological factors included ischaemia and the presence in the blood of certain vasoactive and metabolic depressant substances. It was concluded that the process leading to irreversible shock was multi-factorial in origin but failure appeared to play an important role.
I M Ledingham
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European journal of intensive care medicine     Volume:  2     ISSN:  0340-0964     ISO Abbreviation:  Eur J Intensive Care Med     Publication Date:  1976 Nov 
Date Detail:
Created Date:  1977-01-29     Completed Date:  1977-01-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7504969     Medline TA:  Eur J Intensive Care Med     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  111-7     Citation Subset:  IM    
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MeSH Terms
Angiotensin II / physiology
Catecholamines / blood
Coronary Disease / complications
Endotoxins / adverse effects
Gastrointestinal Hemorrhage / etiology
Heart / physiopathology
Heart Failure / etiology*
Heart Ventricles / physiopathology
Peptides / blood
Shock, Hemorrhagic / complications*
Reg. No./Substance:
0/Catecholamines; 0/Endotoxins; 0/Peptides; 11128-99-7/Angiotensin II

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