Document Detail

Heart diseases and stroke.
MedLine Citation:
PMID:  16469267     Owner:  NLM     Status:  MEDLINE    
A heterogeneous group of heart diseases, varying by cardiac anatomy and physiology, are responsible for a variety of embolic materials that result in cerebral and systemic embolism. Atrial fibrillation accounts for nearly half of all cardioembolic stroke, particularly in the elderly, but in the young congenital septal abnormalities such as patent foramen ovale play a more important role. Therapeutic strategies include stabilization or treatment of the underlying heart disease and prevention of embolism. Oral anticoagulant therapy is indicated for many but decision making on balancing the benefits versus risks can be difficult. New endovascular therapies and devices have become available and await clinical trials that allow them to be compared with existing medical therapies.
Cathy A Sila
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current neurology and neuroscience reports     Volume:  6     ISSN:  1528-4042     ISO Abbreviation:  Curr Neurol Neurosci Rep     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-02-10     Completed Date:  2006-03-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100931790     Medline TA:  Curr Neurol Neurosci Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  23-7     Citation Subset:  IM    
Cerebrovascular Center, Section of Stroke and Neurologic Intensive Care, Cleveland Clinic, 9500 Euclid Avenue S-91, Cleveland, OH 44195, USA.
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MeSH Terms
Aorta / pathology
Atherosclerosis / physiopathology,  therapy
Atrial Fibrillation / physiopathology,  therapy
Cardiomyopathies / physiopathology,  therapy
Clinical Trials as Topic
Heart Aneurysm / physiopathology,  therapy
Heart Diseases* / pathology,  physiopathology,  therapy
Heart Septal Defects, Atrial / physiopathology,  therapy
Stroke* / pathology,  physiopathology,  therapy
Ventricular Dysfunction, Left / physiopathology,  therapy

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