Document Detail

Heart disease in patients with pulmonary embolism.
MedLine Citation:
PMID:  20531195     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: Several heart diseases are promoters of left-side cardiac thrombosis and could lead to arterial embolism. The same mechanism may be responsible for right-side cardiac thrombosis and therefore be a direct source of pulmonary embolism.
RECENT FINDINGS: Yasuoka et al. showed a higher incidence of perfusion defects in lung scan in patients with spontaneous echocontrast in the right atrium than in those without it (40% and 7% respectively; P=0.006). We recently assessed the prevalence of heart diseases in 11.236 consecutive patients older than 60 years discharged from Venetian hospitals with a diagnosis of pulmonary embolism. We observed a higher prevalence of all-cause heart diseases (odds ratio 1.26; 95% confidence interval, 1.13-1.40) in patients with a diagnosis of pulmonary embolism alone (secondary or unprovoked) compared with those discharged with a diagnosis of pulmonary embolism associated with deep vein thrombosis, generating the hypothesis that some specific heart diseases in older patients could themselves be a possible source of pulmonary emboli.
SUMMARY: Further prospective studies are required to confirm these findings, which have the potential to open new horizons for the interpretation and management of venous thromboembolic disease.
Raffaele Pesavento; Chiara Piovella; Paolo Prandoni
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current opinion in pulmonary medicine     Volume:  16     ISSN:  1531-6971     ISO Abbreviation:  Curr Opin Pulm Med     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-07-30     Completed Date:  2010-12-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9503765     Medline TA:  Curr Opin Pulm Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  415-8     Citation Subset:  IM    
Department of Cardiothoracic and Vascular Sciences, 2nd Chair of Internal Medicine, Thromboembolism Unit, University of Padua, Padua, Italy.
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MeSH Terms
Aged, 80 and over
Heart Diseases / complications*,  physiopathology
Middle Aged
Pulmonary Embolism / epidemiology*,  physiopathology
Risk Factors
Venous Thrombosis / complications,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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