Document Detail


Heart block associated with spinocerebellar ataxia type 2.
MedLine Citation:
PMID:  12363174     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 20-year-old man was discharged from the U.S. Army because of increasing gait abnormalities. One year later, he developed episodes of syncope secondary to high-degree atrial/ventricular block with periods of complete heart block and ventricular asystole. A permanent dual-chamber, rate-responsive cardiac pacemaker was implanted. At age 29 years, an abnormal expansion of the CAG trinucleotide repeat in the ataxin-2 gene on chromosome 12 was identified. This case suggests that cardiac conduction abnormalities should be included as part of the recognized clinical heterogeneity of spinocerebellar ataxia type 2.
Authors:
Jack E Riggs
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Military medicine     Volume:  167     ISSN:  0026-4075     ISO Abbreviation:  Mil Med     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-10-04     Completed Date:  2002-12-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2984771R     Medline TA:  Mil Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  795     Citation Subset:  IM    
Affiliation:
Department of Neurology, West Virginia University School of Medicine, Morgantown 26506-9180, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Heart Block / etiology*
Humans
Male
Spinocerebellar Ataxias / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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