| Heart Rate, Heart Rate Variability, and Arrhythmias in Dogs with Myxomatous Mitral Valve Disease. | |
| | |
MedLine Citation:
|
PMID: 22151356 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: Autonomic modulation of heart rhythm is thought to influence the pathophysiology of myxomatous mitral valve disease (MMVD). HYPOTHESES: (1) Holter-derived variables reflecting autonomic modulation of heart rhythm change with MMVD severity in Cavalier King Charles Spaniels (CKCS); (2) Holter-derived variables can identify MMVD severity in CKCS; and (3) Holter-derived variables in CKCS in congestive heart failure (CHF) secondary to MMVD differ from those in dogs of other breeds in CHF. ANIMALS: Ninety privately owned dogs: 70 CKCS with variable MMVD severity and 20 non-CKCS in CHF secondary to MMVD. METHODS: Dogs were prospectively recruited and divided into 5 MMVD severity groups based on history, breed, and physical and echocardiographic examination findings. Holter-derived variables included heart rate variability (HRV), heart rate (HR), and arrhythmia evaluated from 24-hour Holter recordings. RESULTS: In CKCS, 18 of 26 HRV (all P < .0002) and 3 of 9 arrhythmia (all P < .0004) variables decreased with increasing MMVD, whereas minimum and mean HR (all P < .0001) increased with increasing MMVD severity. An arrhythmia variable representing sinus arrhythmia ("premature normals") (P < .0001) and the HRV variable triangular index (TI) (P < .0001) could distinguish CKCS with moderate or severe mitral regurgitation from CKCS in CHF in specific intervals. Among dogs in CHF, Holter-derived variables did not differ among breeds. CONCLUSIONS AND CLINICAL IMPORTANCE: In CKCS, Holter-derived variables changed with MMVD severity. "Premature normals" and TI showed diagnostic potential. Breed differences were not seen among dogs in CHF secondary to MMVD. |
| | |
Authors:
|
C E Rasmussen; T Falk; N E Zois; S G Moesgaard; J Häggström; H D Pedersen; B Ablad; H Y Nilsen; L H Olsen |
Related Documents
:
|
22254826 - Modeling study of the failing heart and its interaction with an implantable rotary bloo... 20153696 - Coronary artery anatomy and apical sparing in apical ballooning syndrome: implications ... 12809396 - A critical evaluation of results of partial left ventriculectomy. 10549906 - Noninvasive visualization of multiple simultaneously activated regions on torso magneto... 19706566 - In utero valvuloplasty for pulmonary atresia with hypoplastic right ventricle: techniqu... 20013626 - Pneumopericardium and pneumomediastinum as a late complication of defibrillator implant... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-12-13 |
Journal Detail:
|
Title: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine Volume: - ISSN: 1939-1676 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2011-12-13 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8708660 Medline TA: J Vet Intern Med Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 by the American College of Veterinary Internal Medicine. |
Affiliation:
|
Department of Basic Animal and Veterinary Sciences. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Contribution of physical education to overall physical activity.
Next Document: Neuromodulation of the pudendal, hypogastric, and tibial nerves with pelvic floor muscle rehabilitat...