Document Detail

Heart failure and the lung.
MedLine Citation:
PMID:  21041971     Owner:  NLM     Status:  MEDLINE    
Heart failure (HF) is a highly prevalent disease that leads to significant morbidity and mortality. There is increasing evidence that the symptoms of HF are exacerbated by its deleterious effects on lung function. HF appears to cause airway obstruction acutely and leads to impaired gas diffusing capacity and pulmonary hypertension in the longer term. It is postulated that this is the result of recurrent episodes of elevated pulmonary capillary pressure leading to pulmonary oedema and pulmonary capillary stress fracture, which produces lung fibrosis. It is likely that impaired lung function impairs the functional status of HF patients and makes them more prone to central sleep apnoea.
Kirk Kee; Matthew T Naughton
Publication Detail:
Type:  Journal Article; Review     Date:  2010-10-28
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  74     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-12-02     Completed Date:  2011-03-09     Revised Date:  2012-01-09    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  2507-16     Citation Subset:  IM    
Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Victoria, Australia.
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MeSH Terms
Airway Obstruction / etiology,  mortality,  physiopathology
Heart Failure / complications,  mortality,  physiopathology*
Hypertension, Pulmonary / etiology,  mortality,  physiopathology
Lung / physiopathology*
Pulmonary Edema / etiology,  mortality,  physiopathology
Pulmonary Fibrosis / etiology,  mortality,  physiopathology
Sleep Apnea Syndromes / etiology,  mortality,  physiopathology

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