Document Detail

Hearing evaluation with distortion-product otoacoustic emissions in young patients undergoing haemodialysis.
MedLine Citation:
PMID:  11437849     Owner:  NLM     Status:  MEDLINE    
Sensorineural hearing loss is frequently reported in young patients with chronic renal failure having haemodialysis. The effect of a single session of haemodialysis on hearing acuity was assessed prospectively in nine children with end-stage renal disease using pure-tone audiometry (PTA) and distortion-product otoacoustic emissions (DPOAEs). Results were compared with those obtained from nine audiologically normal healthy children also tested with PTA and DPOAEs twice during a 4-h interval. Sensorineural hearing loss of unknown aetiology was found in 55.5% of renal patients, mainly in the higher frequencies. Patients on HD had mean PTA thresholds significantly poorer than those of the control group in the frequency range 1000-12 000Hz (P < 0.05). Their mean DPOAE amplitudes were significantly lower in all frequencies > 1184 Hz (P < 0.05). Furthermore, patients' ears with normal PTA thresholds between 250 and 4000 Hz also had decreased DPOAE amplitudes. No significant changes in PTA thresholds or DPOAE amplitudes were encountered in renal patients before and after a HD session (P > 0.05). Changes in PTA thresholds or DPOAE amplitudes were not significantly different than those in the control group (P > 0.05). In conclusion, sensorineural hearing loss of unknown origin, especially in high frequencies, is frequent in young renal patients under HD and single HD sessions do not seem to alter the hearing acuity of these patients. DPOAEs seem to be more sensitive to incipient cochlear damage than behaviour thresholds in monitoring renal patients.
P Stavroulaki; T P Nikolopoulos; I Psarommatis; N Apostolopoulos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical otolaryngology and allied sciences     Volume:  26     ISSN:  0307-7772     ISO Abbreviation:  Clin Otolaryngol Allied Sci     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-07-04     Completed Date:  2001-08-23     Revised Date:  2005-05-02    
Medline Journal Info:
Nlm Unique ID:  7701793     Medline TA:  Clin Otolaryngol Allied Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  235-42     Citation Subset:  IM    
Department of Otorhinolaryngology Head and Neck Surgery, Children's Hospital 'P. & A. Kyriakou', Athens, Greece.
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MeSH Terms
Audiometry, Pure-Tone
Hearing Loss, Sensorineural / diagnosis*,  etiology
Hearing Tests*
Kidney Failure, Chronic / complications,  therapy
Otoacoustic Emissions, Spontaneous*
Prospective Studies
Renal Dialysis* / adverse effects

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