Document Detail

Health status and productive performance of somatic cell cloned cattle and their offspring produced in Japan.
MedLine Citation:
PMID:  18319570     Owner:  NLM     Status:  MEDLINE    
Since the first somatic cell cloned calves were born in Japan in 1998, more than 500 cloned cattle have been produced by somatic cell nuclear transfer and many studies concerning cloned cattle and their offspring have been conducted in this country. However, most of the results have been published in Japanese; thus, the data produced in this country is not well utilized by researchers throughout the world. This article reviews the 65 reports produced by Japanese researchers (62 written in Japanese and 3 written in English), which employed 171 clones and 32 offspring, and categorizes them according to the following 7 categories: (1) genetic similarities and muzzle prints, (2) hematology and clinical chemistry findings, (3) pathology, (4) growth performance, (5) reproductive performance, (6) meat production performance and (7) milk production performance. No remarkable differences in health status or reproductive performance were found among conventionally bred cattle, somatic cell cloned cattle surviving to adulthood and offspring of somatic cell cloned cattle. Similarities in growth performance and meat quality were observed between nuclear donor cattle and their clones. The growth curves of the offspring resembled those of their full siblings.
Shinya Watanabe; Takashi Nagai
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Journal of reproduction and development     Volume:  54     ISSN:  0916-8818     ISO Abbreviation:  J. Reprod. Dev.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-03-05     Completed Date:  2008-05-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9438792     Medline TA:  J Reprod Dev     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  6-17     Citation Subset:  IM    
National Institute of Livestock and Grassland Science, Tsukuba 305-0901, Japan.
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MeSH Terms
Cattle / abnormalities,  physiology*
Cloning, Organism / adverse effects,  veterinary*
Health Status*
Meat / standards*
Milk / standards
Reproduction / physiology*

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