Document Detail

Health-related quality of life following decompression compared to decompression and fusion for degenerative lumbar spondylolisthesis: a Canadian multicentre study.
MedLine Citation:
PMID:  25078938     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Decompression alone (D) is a well-accepted treatment for patients with lumbar spinal stenosis (LSS) causing neurogenic claudication; however, D is controversial in patients with LSS who have degenerative spondylolisthesis (DLS). Our goal was to compare the outcome of anatomy-preserving D with decompression and fusion (DF) for patients with grade I DLS. We compared patients with DLS who had elective primary 1-2 level spinal D at 1 centre with a cohort who had 1-2 level spinal DF at 5 other centres.
METHODS: Patients followed for at least 2 years were included. Primary analysis included comparison of change in SF-36 physical component summary (PCS) scores and the proportion of patients achieving minimal clinically important difference (MCID) and substantial clinical benefit (SCB).
RESULTS: There was no significant difference in baseline SF-36 scores between the groups. The average change in PCS score was 10.4 versus 11.4 (p = 0.61) for the D and DF groups, respectively. Sixty-seven percent of the D group and 71% of the DF group attained MCID, while 64% of both D and DF groups attained SCB. There was no significant difference between D and DF for change in PCS score (p = 0.74) or likelihood of reaching MCID (p = 0.81) or SCB (p = 0.85) after adjusting for other variables.
CONCLUSION: In select patients with DLS, the outcome of D is comparable to DF at a minimum of 2 years.
Abstract available from the publisher.
Y Raja Rampersaud; Charles Fisher; Albert Yee; Marcel F Dvorak; Joel Finkelstein; Eugene Wai; Edward Abraham; Stephen J Lewis; David Alexander; William Oxner
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Multicenter Study    
Journal Detail:
Title:  Canadian journal of surgery. Journal canadien de chirurgie     Volume:  57     ISSN:  1488-2310     ISO Abbreviation:  Can J Surg     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-08-01     Completed Date:  2014-09-22     Revised Date:  2014-09-24    
Medline Journal Info:
Nlm Unique ID:  0372715     Medline TA:  Can J Surg     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  E126-33     Citation Subset:  IM    
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MeSH Terms
Combined Modality Therapy
Decompression, Surgical*
Follow-Up Studies
Linear Models
Logistic Models
Lumbar Vertebrae / surgery*
Middle Aged
Multivariate Analysis
Retrospective Studies
Spinal Fusion*
Spondylolisthesis / surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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