Document Detail

Health-related quality of life after surgery for advanced and recurrent rectal cancer: a nationwide prospective study.
MedLine Citation:
PMID:  24373460     Owner:  NLM     Status:  Publisher    
AIM: Advances in the treatment of rectal cancer have made it possible to perform complex rectal cancer surgery (COMP-RCS) in patients with primary advanced rectal cancer penetrating beyond the total mesorectal excision planes and in patients with locally recurrent rectal cancer. The aim of this study was to examine Health-related Quality of Life (HRQoL) before and during the first two years after surgery with COMP-RCS.
METHOD: Between 2001-2008, 180 patients were treated with COMP-RCS at Aarhus University Hospital. HRQoL was assessed preoperatively and 3, 6, 12, 18 and 24 months after surgery using three questionnaires. The results were compared with patients treated with standard rectal cancer surgery (STAN-RCS) and to data from the general Danish population (NORM-DATA).
RESULTS: 122 (68%) patients responded to the questionnaires. Of these eighty (66%) with disease-free survival two years after surgery were included in the main analysis. The lowest level of functioning and the highest degree of symptoms were reported preoperatively. The majority of the HRQoL scales improved or remained stable during the first postoperative year; a decrease was observed for body image only. One year after surgery, HRQoL in patients treated with COMP-RSC was comparable to patients treated with STAN-RCS. Lower levels were found for physical and emotional role functioning, compared to NORM-DATA.
CONCLUSION: Patients treated with COMP-RCS experienced improvement in HRQoL in the first year after surgery. One year after surgery, HRQoL was similar to patients treated with STAN-RCS. Compared to NORM-DATA, lower levels were found for physical and emotional role functioning. This article is protected by copyright. All rights reserved.
H V Thaysen; P Jess; P C Rasmussen; M B Nielsen; Søren Laurberg
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-12-26
Journal Detail:
Title:  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland     Volume:  -     ISSN:  1463-1318     ISO Abbreviation:  Colorectal Dis     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-12-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883611     Medline TA:  Colorectal Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
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