Document Detail

Health-related Quality of Life Outcomes After Robot-assisted and Open Radical Cystectomy Using a Validated Bladder-specific Instrument: A Multi-institutional Study.
MedLine Citation:
PMID:  24746661     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To evaluate health-related quality of life (HRQL) using validated bladder-specific Bladder Cancer Index (BCI) and European Organization for Research and Treatment of Cancer Body Image scale (BIS) between open radical cystectomy (ORC) and robot-assisted radical cystectomy (RARC).
METHODS: This was a retrospective case series of all patients who underwent radical cystectomy. Patients were grouped based on surgical approach (open vs robot assisted) and diversion technique (extracorporeal vs intracorporeal). Patients completed BCI and BIS preoperatively and at standardized postoperative intervals (at least 2). The primary exposure variable was surgical approach. The primary outcome measure was difference in interval and baseline BCI and BIS scores in each group. The Fisher exact, Wilcoxon rank-sum, and Kruskal-Wallis tests were used for comparisons.
RESULTS: Eighty-two and 100 patients underwent RARC and ORC, respectively. Compared with RARC, more patients undergoing ORC had an American Society of Anesthesiology score ≥3 (66% vs 45.1% RARC; P = .007) and shorter median operative time (350 vs 380 minutes; P = .009). Baseline urinary, bowel, sexual function, and body image were not different between both the groups (P = 1.0). Longitudinal postoperative analysis revealed better sexual function in ORC group (P = .047), with no significant differences between both the groups in the other 3 domains (P = .11, .58, and .93). Comparisons regarding diversion techniques showed similar findings in baseline and postoperative HRQL data, with no significant differences in the HRQL and body image domains.
CONCLUSION: RARC has comparable HRQL outcomes to ORC using validated BCI and BIS. The diversion technique used does not seem to affect patients' quality of life.
Ahmed A Aboumohamed; Syed Johar Raza; Ali Al-Daghmin; Christopher Tallman; Terrance Creighton; Heather Crossley; Stephen Dailey; Aabroo Khan; Rakeeba Din; Diana Mehedint; Katy Wang; Yi Shi; Mohamed Sharif; Gregory Wilding; Alon Weizer; Khurshid A Guru
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-4-17
Journal Detail:
Title:  Urology     Volume:  -     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-4-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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