Document Detail

Health effects of toluene exposure.
MedLine Citation:
PMID:  3359818     Owner:  NLM     Status:  MEDLINE    
The impact of industrial toluene exposure was assessed in 262 male employees of two Danish photographic printing plants. The study involved assessment of acute and chronic exposure based on a scoring system, standardised questions, measurement of blood pressure, pulmonary functions, and the plasma concentrations of urate, creatinine, creatine kinase, alanine-aminotransferase, FSH, LH, testosterone, sexual hormone binding globulin, thyroxine, triiodothyronine, and cortisole (following synacthen). The potentially confounding factors: age, weight, height, alcohol consumption and tobacco smoking were included in statistical analysis which showed that systolic blood pressure (p less than 0.01), P-P-FSH (p less than 0.001), dizziness (p less than 0.0001), decreased ability to concentrate (p less than 0.001), and dizziness during the past year (p less than 0.01) were correlated with the exposure score. Following six weeks without exposure, systolic blood pressure and P-ALAT decreased, the latter being correlated with the exposure score.
H I Mørck; P Winkel; F Gyntelberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Danish medical bulletin     Volume:  35     ISSN:  0907-8916     ISO Abbreviation:  Dan Med Bull     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-06-03     Completed Date:  1988-06-03     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066040     Medline TA:  Dan Med Bull     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  196-200     Citation Subset:  IM    
Department of Clinical Chemistry, Rigshospitalet, University Hospital, Copenhagen, Denmark.
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MeSH Terms
Blood Chemical Analysis
Blood Pressure
Dizziness / chemically induced
Environmental Exposure*
Hormones / blood
Middle Aged
Occupational Diseases / chemically induced*,  diagnosis
Physical Examination
Respiratory Function Tests
Toluene / administration & dosage*
Reg. No./Substance:
0/Hormones; 108-88-3/Toluene

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