Document Detail


Health effects of garlic.
MedLine Citation:
PMID:  16035690     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Garlic has long been used medicinally, most recently for its cardiovascular, antineoplastic, and antimicrobial properties. Sulfur compounds, including allicin, appear to be the active components in the root bulb of the garlic plant. Studies show significant but modest lipid-lowering effects and antiplatelet activity. Significant blood pressure reduction is not consistently noted. There is some evidence for antineoplastic activity and insufficient evidence for clinical antimicrobial activity. Side effects generally are mild and uncommon. Garlic appears to have no effect on drug metabolism, but patients taking anticoagulants should be cautious. It seems prudent to stop taking high dosages of garlic seven to 10 days before surgery because garlic can prolong bleeding time.
Authors:
Ellen Tattelman
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  American family physician     Volume:  72     ISSN:  0002-838X     ISO Abbreviation:  Am Fam Physician     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-07-22     Completed Date:  2005-08-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1272646     Medline TA:  Am Fam Physician     Country:  United States    
Other Details:
Languages:  eng     Pagination:  103-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Family and Social Medicine, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10467, USA. etattelm@montefiore.org
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MeSH Terms
Descriptor/Qualifier:
Animals
Bleeding Time
Clinical Trials as Topic
Drug Evaluation, Preclinical
Evidence-Based Medicine
Food-Drug Interactions
Garlic* / adverse effects,  chemistry,  physiology
Humans
Hyperlipidemias / prevention & control
Hypertension / prevention & control
Infection Control
Neoplasms / prevention & control
Phytotherapy / adverse effects,  methods*,  standards
Research Design / standards

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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