| The health implications of sucrose, high-fructose corn syrup, and fructose: what do we really know? | |
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MedLine Citation:
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PMID: 20663468 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The epidemic of obesity and related metabolic diseases continues to extract an enormous health toll. Multiple potential causes for obesity have been suggested, including increased fat consumption, increased carbohydrate consumption, decreased physical activity, and, most recently, increased fructose consumption. Most literature cited in support of arguments suggesting a link between obesity and fructose consumption is epidemiologic and does not establish cause and effect. The causes of obesity are well-known and involve the overconsumption of calories from all sources. Research employing a pure fructose model distorts the real-world situation of fructose consumption, which predominantly comes from sweeteners containing roughly equal proportions of glucose and fructose. The fructose hypothesis has the potential to distract us from further exploration and amelioration of known causes of obesity. Randomized prospective trials of metabolic consequences of fructose consumption at normal population levels and from sources typically found in the human diet such as sucrose and high-fructose corn syrup are urgently needed. |
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Authors:
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James M Rippe |
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Publication Detail:
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Type: Journal Article Date: 2010-07-01 |
Journal Detail:
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Title: Journal of diabetes science and technology Volume: 4 ISSN: 1932-2968 ISO Abbreviation: J Diabetes Sci Technol Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-28 Completed Date: 2010-11-04 Revised Date: 2011-08-01 |
Medline Journal Info:
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Nlm Unique ID: 101306166 Medline TA: J Diabetes Sci Technol Country: United States |
Other Details:
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Languages: eng Pagination: 1008-11 Citation Subset: IM |
Copyright Information:
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2010 Diabetes Technology Society. |
Affiliation:
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Rippe Lifestyle Institute, Shrewsbury, Massachusetts 01545, USA. bgrady@rippelifestyle.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Fructose
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adverse effects* Humans Metabolic Diseases / complications, epidemiology Metabolism / drug effects Obesity / epidemiology*, etiology Sucrose / adverse effects* Zea mays / chemistry* |
| Chemical | |
Reg. No./Substance:
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30237-26-4/Fructose; 57-50-1/Sucrose |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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