Document Detail


Healing of stoma orifices: multicenter, prospective, randomized study comparing calcium alginate mesh and polyvidone iodine mesh.
MedLine Citation:
PMID:  19603229     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The aim of this multicenter, randomized, prospective study was to reveal a difference in terms of a guided healing period in the case of stoma orifices after reestablishing digestive continuity by comparing an alginate mesh with a polyvidone iodine mesh. METHODS: Between April 2004 and September 2005, a total of 73 patients were randomized into two groups: A (alginate mesh) and M (polyvidone iodine mesh). The groups were comparable for demographic data, indications for and the type of stoma, and perioperative data. The main evaluation criterion was percentage healing at the 28th postoperative day (D28); and the secondary criteria were healing time, rate of infectious complications, and number of dressing changes applied. RESULTS: The mean percentage healing at D28 was 91% in group A and 87% in group M (p = 0.49). The mean healing time was 31 days in group A and 32 days in group M (p = 0.80). One parietal abscess (3%) occurred in group A (p = 0.37). The mean number of meshes used was 13 +/- 5 in group A and 18 +/- 8 in group M (p < 0.005). CONCLUSION: The use of an alginate mesh for guided healing of stoma orifices after reestablishing digestive continuity allows effective healing within a normal period of time with a lower number of meshes.
Authors:
Olivier Brehant; Patrick Pessaux; Nicolas Regenet; Jean Jacques Tuech; Fabrizio Panaro; Georges Mantion; Vincent Tassetti; Paul Antoine Lehur; Jean Pierre Arnaud
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial    
Journal Detail:
Title:  World journal of surgery     Volume:  33     ISSN:  1432-2323     ISO Abbreviation:  World J Surg     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-17     Completed Date:  2009-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704052     Medline TA:  World J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1795-801     Citation Subset:  IM    
Affiliation:
Digestive Surgery Department, University Hospital, 4 rue Larrey, Angers, 49000, France.
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MeSH Terms
Descriptor/Qualifier:
Alginates / pharmacology*
Bandages*
Biocompatible Materials / pharmacology*
Chi-Square Distribution
Female
Glucuronic Acid / pharmacology
Hexuronic Acids / pharmacology
Humans
Male
Middle Aged
Povidone-Iodine / pharmacology*
Prospective Studies
Statistics, Nonparametric
Surgical Mesh*
Surgical Stomas*
Surgical Wound Infection / epidemiology,  prevention & control
Treatment Outcome
Wound Healing / drug effects*
Chemical
Reg. No./Substance:
0/Alginates; 0/Biocompatible Materials; 0/Hexuronic Acids; 25655-41-8/Povidone-Iodine; 576-37-4/Glucuronic Acid; 9005-32-7/alginic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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