Document Detail

Headache and epilepsy.
MedLine Citation:
PMID:  23801004     Owner:  NLM     Status:  In-Data-Review    
Headache and epilepsy often co-occur. Epidemiologic studies conducted in the past few years reinforce the notion of a bi-directional association between migraine and epilepsy. Data on an association between headache (in general) and epilepsy, however, are less clear. Peri-ictal headache often presents with migraine-like symptoms and can be severe. A correct diagnosis and management are paramount. It was demonstrated that cortical hyperexcitability may underlie both epilepsy and migraine. A recent study linked spreading depolarisation, the supposed underlying pathophysiological mechanism of migraine with aura, to epilepsy. Although this study was carried out in patients who had suffered a subarachnoid haemorrhage, the finding may shed light on pathophysiological mechanisms common to epilepsy and migraine.
P R Bauer; J A Carpay; G M Terwindt; J W Sander; R J Thijs; J Haan; G H Visser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current pain and headache reports     Volume:  17     ISSN:  1534-3081     ISO Abbreviation:  Curr Pain Headache Rep     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-06-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100970666     Medline TA:  Curr Pain Headache Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  351     Citation Subset:  IM    
SEIN Epilepsy Institute in the Netherlands Foundation, Heemstede, The Netherlands, P.O. Box 540, 2130 AM, Hoofddorp, The Netherlands.
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