Document Detail

Head ultrasonograhy as a screening tool in apparently healthy asymptomatic term neonates.
MedLine Citation:
PMID:  21446229     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The rate of brain abnormalities in asymptomatic term neonates varies substantially in previous studies. Some of these rates may justify general screening of healthy newborns by head ultrasound (HUS).
OBJECTIVES: To assess the incidence of intracranial abnormalities among asymptomatic term newborns with HUS and to detect high-risk populations that might need such screening.
METHODS: This was a prospective study in 493 term newborns who underwent HUS and a neurological evaluation during the first 3 days of life. The neurological examination results were unknown to the sonographist and the examiner was blinded to the HUS findings. The abnormal HUS findings were classified as significant or non-significant according to the current literature.
RESULTS: Abnormal HUS was found in 11.2% of the neonates. Significant findings were noted in 3.8% of the infants. There was no association between non-structural HUS findings (hemorrhage or echogenicity) and mode of delivery. There was no relationship between any HUS abnormality and birth weight, head circumference and maternal age, ethnicity, education or morbidity. The rate of abnormal neurological, hearing or vision evaluation in infants with a significant abnormal HUS (5.2%) was comparable to the rate in infants with normal or non-significant findings on HUS (3.1%).
CONCLUSIONS: There is no indication for routine HUS screening in apparently healthy term neonates due to the relatively low incidence of significant brain abnormalities in these infants in our population.
Ayala Gover; David Bader; Martha Weinger-Abend; Irena Chystiakov; Elka Miller; Arieh Riskin; Ori Hochwald; Liana Beni-Adani; Emanuel Tirosh; Amir Kugelman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Israel Medical Association journal : IMAJ     Volume:  13     ISSN:  1565-1088     ISO Abbreviation:  Isr. Med. Assoc. J.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-03-30     Completed Date:  2011-05-31     Revised Date:  2012-08-15    
Medline Journal Info:
Nlm Unique ID:  100930740     Medline TA:  Isr Med Assoc J     Country:  Israel    
Other Details:
Languages:  eng     Pagination:  9-13     Citation Subset:  IM    
Department of Neonatology, Bnai Zion Medical Center affiliated with Rappaport Faculty of Medicine, Technion, Haifa, Israel.
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MeSH Terms
Birth Weight
Brain Diseases / complications,  epidemiology,  ultrasonography*
Gestational Age
Infant, Newborn
Neonatal Screening*
Neurologic Examination
Prospective Studies
Risk Factors
Comment In:
Isr Med Assoc J. 2012 Jun;14(6):403-4   [PMID:  22891412 ]

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