Document Detail

Head-to-head comparison of multislice computed tomography and exercise electrocardiography for diagnosis of coronary artery disease.
MedLine Citation:
PMID:  16880194     Owner:  NLM     Status:  MEDLINE    
AIMS: To prospectively compare multislice computed tomography (MSCT) and exercise electrocardiography (ex-ECG) for diagnosis of coronary artery disease (CAD) with conventional coronary angiography as the reference standard. METHODS AND RESULTS: A consecutive cohort of 80 patients with suspected CAD was examined with MSCT using 16 x 0.5 mm detector collimation, ex-ECG, and conventional coronary angiography according to standard protocols. Results were compared using the paired McNemar's test, the chi(2) test, and 95%CIs. Both the sensitivity and specificity of MSCT [91% (40 of 44 patients, 95%CI 78-97%) and 83% (30 of 36 patients, 95%CI 67-94%)] were significantly higher (P = 0.039 and P < 0.001) than those for ex-ECG [73% (32 of 44 patients, 95%CI 57-85%) and 31% (11 of 36 patients, 95%CI 16-48%)]. The pairwise McNemar's test showed significant differences between MSCT and ex-ECG in the overall diagnosis in patients with suspected CAD (P = 0.036). The rate of non-diagnostic examinations was not significantly (P = 0.078) different between MSCT and ex-ECG [8% (6 of 80 patients, 95%CI 3-16%) vs. 19% (15 of 80 patients, 95%CI 11-29%)]. CONCLUSION: In this consecutive cohort of patients scheduled to undergo conventional coronary angiography, the performance of MSCT for diagnosis of CAD was superior to that of ex-ECG.
Marc Dewey; Hans-Peter Dübel; Tania Schink; Gert Baumann; Bernd Hamm
Related Documents :
16169354 - Relation of aspirin resistance to coronary flow reserve in patients undergoing elective...
8049984 - Angiographic findings of silent ischaemia following aortocoronary bypass surgery.
18035074 - Association of polymorphisms in platelet and hemostasis system genes with acute myocard...
11923034 - Limited role of coronary angioplasty and stenting in coronary spastic angina with organ...
18395294 - Alefacept for moderate to severe atopic dermatitis: a pilot study in adults.
8555074 - Decreased production of interferon gamma by anti-cd3 monoclonal antibody and interleuki...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-07-31
Journal Detail:
Title:  European heart journal     Volume:  28     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-10-22     Completed Date:  2008-04-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  England    
Other Details:
Languages:  eng     Pagination:  2485-90     Citation Subset:  IM    
Department of Radiology, Medical School, Humboldt-Universität zu Berlin, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Coronary Angiography / methods*
Coronary Artery Disease / diagnosis*,  pathology,  radiography
Electrocardiography / methods*
Exercise Test / methods
Middle Aged
Reference Values
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pharmacological prevention of serious anaphylactic reactions due to iodinated contrast media: system...
Next Document:  The cost effectiveness of behavioural graded activity in patients with osteoarthritis of hip and/or ...