Document Detail


Head and neck paragangliomas: value of contrast-enhanced 3D MR angiography.
MedLine Citation:
PMID:  18339724     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND PURPOSE: A rapid and accurate MR imaging technique would be beneficial to assess paragangliomas in the head and neck and to distinguish them from other lesions. The purpose of this study was to determine whether the combination of elliptic centric contrast-enhanced MR angiography (CE-MRA) and unenhanced and enhanced spin-echo imaging (conventional MR imaging) is more accurate than conventional MR imaging alone to assess paragangliomas in the head and neck. MATERIALS AND METHODS: Three radiologists retrospectively and independently reviewed CE-MRA and conventional MR imaging in 27 patients with suspected paragangliomas. The overall image quality and the probability of paraganglioma were recorded. The results of each technique and their combination were analyzed for sensitivity and specificity. Receiver operating characteristic (ROC) analyses were performed by using histologic analysis, imaging, and/or clinical findings as the reference standard. RESULTS: Forty-six lesions were found in 27 patients. In the assessment of paragangliomas, the combination of conventional MR imaging and CE-MRA was significantly superior to conventional MR imaging alone. Sensitivity and specificity respectively were the following: for CE-MRA, 100% and 94%; and for conventional MR imaging, 94% and 41%. The specificity of CE-MRA was significantly higher than that of conventional MR imaging (P = .004). There was good-to-excellent interobserver agreement for the paraganglioma probability with CE-MRA (nonweighted kappa, 0.67-0.77), whereas there was fair-to-good interobserver agreement with conventional MR imaging (nonweighted kappa, 0.50-0.65). CONCLUSION: In combination with conventional MR imaging, CE-MRA yields an excellent diagnostic value for the assessment of head and neck paragangliomas; hence, the 2 techniques should be regarded as complementary.
Authors:
F Neves; L Huwart; G Jourdan; D Reizine; P Herman; E Vicaut; J P Guichard
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2008-03-13
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  29     ISSN:  1936-959X     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-14     Completed Date:  2008-06-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  883-9     Citation Subset:  IM    
Affiliation:
Department of Neuroradiology, Groupe Hospitalier Lariboisière-Fernand-Widal AP-HP, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Contrast Media
Female
Head and Neck Neoplasms / diagnosis*
Humans
Image Enhancement / methods*
Magnetic Resonance Angiography / methods*
Male
Meglumine / diagnostic use*
Middle Aged
Observer Variation
Organometallic Compounds / diagnostic use*
Paraganglioma / diagnosis*
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 0/gadoterate meglumine; 6284-40-8/Meglumine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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