| Head and neck cancer: Value of perfusion CT in depicting primary tumor spread. | |
| | |
MedLine Citation:
|
PMID: 22293874 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Background: The aim of this study was to assess head and neck squamous cell cancer and surrounding tissue in computed tomography contrast enhanced and perfusion studies, and to examine the role of perfusion imaging in depiction of tissue infiltration.<br /> Material/Methods: We prospectively evaluated 43 primary malignant head and neck tumors, using standard CT followed by perfusion. Blood flow, blood volume, mean transit time, and permeability values were obtained using regions of interest (ROIs) over lesions and surrounding tissue. Results were compared with histological analysis of resected tissue. Sensitivity, specificity, accuracy, positive and negative predictive values were calculated for both methods.<br /> Results: We found significant differences between infiltrated and non-infiltrated tissue, especially with regard to muscles. In case of bone and salivary gland infiltration, change in perfusion parameters did not allow proper diagnosis.<br /> Conclusions: CTP shows promise in depicting malignant infiltration. The combined use of CECT plus CTP results in correct staging of the majority of head and neck tumors.<br /> |
| | |
Authors:
|
Agnieszka Trojanowska; Piotr Trojanowski; Andrzej Drop; Tomasz Jargiełło; Janusz Klatka |
Related Documents
:
|
18514954 - Recent trends in utilization rates of abdominal imaging: the relative roles of radiolog... 19830474 - Abdominal pain in a young woman (2009: 8b). 8677314 - Ct scan of mesentery-omentum peritoneum. 18581024 - Ct findings of tuberculous peritonitis. 8755494 - Magnetic resonance microscopy and spectroscopy reveal kinetics of cryoprotectant permea... 21661754 - Monodisperse magnetic nanoparticles for theranostic applications. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Medical science monitor : international medical journal of experimental and clinical research Volume: 18 ISSN: 1643-3750 ISO Abbreviation: Med. Sci. Monit. Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-02-01 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9609063 Medline TA: Med Sci Monit Country: Poland |
Other Details:
|
Languages: eng Pagination: CR112-118 Citation Subset: IM |
Affiliation:
|
1st Department of Diagnostic Radiology, Medical University in Lublin, Lublin, Poland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The influence of heparin resistance on postoperative complications in patients undergoing coronary s...
Next Document: Self-esteem and styles of coping with stress versus strategies of planning in people with psychopath...