Document Detail

Head circumference at birth and exposure to tobacco, alcohol and illegal drugs during early pregnancy.
MedLine Citation:
PMID:  22002105     Owner:  NLM     Status:  Publisher    
AIMS: We aimed to assess the effects of exposure to tobacco smoke, alcohol and illegal drugs during early pregnancy on the head circumference (HC) at birth of otherwise healthy neonates. METHODS: A follow-up study from the first trimester of pregnancy to birth was carried out in 419 neonates. An environmental reproductive health form was used to record data of substance exposure obtained during the first obstetric visit at the end of the first trimester. A multiple linear regression model was created for this purpose. RESULTS: Alcohol intake during pregnancy and medical ionizing radiation exposure were the most significant predictors of HC. The mothers' alcohol consumption increased with the mothers' and fathers' education level, net family income and fathers' alcohol consumption. In contrast, maternal smoking decreased with increasing mothers' and fathers' education level and net family income. About 13% of the surveyed embryos were exposed to illegal drugs. CONCLUSIONS: Mild to moderate alcohol consumption diminishes the at-birth HC of theoretically healthy newborns in a linear form. There was no threshold dose. We perceived a need for increasing the awareness, and for training, of health care professionals and parents, in regard to risks of alcohol consumption and for recommending abstinence of these substances in both parents during pregnancy. It should also be remembered that medical ionizing radiation should be performed only during the first half of the cycle in fertile women. We think that our study has an important social impact as it affords data for implementing policies for promoting "healthy pregnancies".
Juan A Ortega-García; Jorge E Gutierrez-Churango; Miguel F Sánchez-Sauco; Miguel Martínez-Aroca; Juan L Delgado-Marín; M Sánchez-Solis; J J Parrilla-Paricio; Luz Claudio; Juan F Martínez-Lage
Related Documents :
3276195 - The yolk sac in early pregnancy failure.
15916665 - Maternal steroid enhancement of fetal rabbit gastrointestinal motility.
15222515 - First trimester umbilical cord and vessel diameters of thai fetuses.
2408225 - Real-time ultrasonography for pregnancy diagnosis and estimation of fetal age in farmed...
16413275 - Analysis of the interaction between cytohesin 2 and ipcef1.
6542235 - Suppression of postpartum fertility in pairs of female rats sharing the same nesting en...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-15
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  -     ISSN:  1433-0350     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Pediatric Environmental Health Specialty Unit, Virgen de la Arrixaca University Hospital, 30120, El Palmar, Murcia, Spain,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Challenges in diagnosing SSPE.
Next Document:  Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular...