| Head and Neck Lymphatic Malformation Treatment: A Systematic Review. | |
| | |
MedLine Citation:
|
PMID: 22785242 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
ObjectiveTo systematically review literature pertaining to head and neck lymphatic malformation treatment and to use individual-level data presented in qualifying case series to describe the reported efficacy, complications, and functional impact of surgery and sclerotherapy. The authors evaluated whether treatment modalities differ by lymphatic malformation stage.Data SourcesThe terms lymphangioendothelioma, lymphangioma, cystic hygroma, and malformation were used to perform an Ovid literature search yielding 6292 references. The authors excluded references that did not involve head and neck lymphatic malformation treatment, include at least 5 patients, follow patients 1 year, define treatment modality, and state complications.Review MethodsThe authors summarized data from 1205 patients reported in 41 articles. Individual-level data, in the 29 articles reporting these data, were pooled and tabulated.ResultsThe absence of within-study comparisons of treatment success, as well as the range of reporting methods, precluded a formal meta-analysis. Most reports were case series (37; 90%). The primary treatment modality was sclerotherapy in 17 (41%), surgery in 16 (39%), or surgery combined with other modalities in 9 (20%). Individual-level data were captured for 283 patients. No treatment modality clearly resulted in superior treatment outcome. Complications were more frequent in surgical series but were reported inconsistently in sclerotherapy studies.ConclusionThere is evidence that lymphatic malformation treatment can be done effectively with surgery or sclerotherapy, but further study is necessary to determine which is superior. Standardized guidelines for reporting lymphatic malformation case series do not currently exist, making comparison of treatment outcomes of differing treatment modalities difficult. |
| | |
Authors:
|
Mary Theresa Adams; Babette Saltzman; Jonathan A Perkins |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-7-11 |
Journal Detail:
|
Title: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Volume: - ISSN: 1097-6817 ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
|
Created Date: 2012-7-12 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8508176 Medline TA: Otolaryngol Head Neck Surg Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Otolaryngology, Madigan Army Medical Center, Tacoma, Washington, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Etiologic Diagnosis of Nonsyndromic Genetic Hearing Loss in Adult vs Pediatric Populations.
Next Document: Long-Term Survival in a Dog with Anaplastic Oligodendroglioma Treated with Radiation Therapy and CCN...