| HbSC hemoglobinopathy suspected by chest x-ray and red blood cell morphology. | |
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MedLine Citation:
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PMID: 16502600 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thorax scan was performed for elucidation of a pulmonary problem in a Nigerian immigrant. The aspect of the vertebrae suggested sickle cell disease, of course without specification of the genotype. Routine hematological tests seemed compatible with an HbSC disease, showing typical laboratory features, namely a significant proportion of hyperchromic RBC, corresponding to secondary, non hereditary spherocytosis, presence of numerous target cells and occasional HbC crystals on Pappenheim stained blood films. The diagnosis of HbSC disease was confirmed by HPLC, iso-electric focusing and citrate agar electrophoresis of hemoglobin and by reverse phase HPLC of globin-chains. This case illustrates the importance of screening for hemoglobin anomalies as it is performed in a multiethnic country such as the Grand Duchy of Luxembourg |
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Authors:
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J Thoma; D Kutter; S Casel; P Rosoux; C Braas; F Ries; P Groff; G Kalmes; B Golinska |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta clinica Belgica Volume: 60 ISSN: 0001-5512 ISO Abbreviation: Acta Clin Belg Publication Date: 2005 Nov-Dec |
Date Detail:
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Created Date: 2006-02-28 Completed Date: 2006-04-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370306 Medline TA: Acta Clin Belg Country: Belgium |
Other Details:
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Languages: eng Pagination: 377-82 Citation Subset: IM |
Affiliation:
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Laboratoires réunis, L6101 Junglinster, Grand Duchy of Luxembourg. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Erythrocytes / pathology* Hemoglobin SC Disease / pathology*, radiography* Humans Male Thoracic Vertebrae / radiography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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