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Is HbA1c a risk factor for type 2 diabetic subjects without macro and micro vascular complications?
MedLine Citation:
PMID:  22295973     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Objective: Our study attempted to evaluate the diagnostic value of HbA1c in predicting diabetic dyslipidemia and cardiovascular diseases (CVD). Methods: Study comprised 229 subjects (156 males and 73 females) with diabetic dyslipidemia without any micro and macro vascular disorders. Fasting blood samples were taken to analyse biochemical parameters like HbA1c, sugar and lipid profile. Results: The HbA1c levels did not differ much between males (6.96 ± 1.11) and females (7.01 ± 1.19). HbA1c demonstrated a positive significant correlation with cholesterol, LDL and a negative significant correlation with HDL. Patients with HbA1c >7.0 % had significantly higher value of cholesterol, LDL when compared with <7.0%. Conclusions: The findings of this study clearly suggest that HbA1c endures the ability of predicting CVD risk in the diabetic patients without any micro and macro vascular disorder. Therefore study recommends using HbA1c as a marker for predicting the risk of developing CVD.
Authors:
Geetha Bhaktha; B Shivananda Nayak; Sreemathi Mayya; Manjula Shantaram
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-2
Journal Detail:
Title:  Archives of physiology and biochemistry     Volume:  -     ISSN:  1744-4160     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9510153     Medline TA:  Arch Physiol Biochem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Biochemistry, Yenepoya Medical College, Yenepoya University , Mangalore, Karnataka , India.
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