| HbA1C - overall glycemia marker and hemolytic anemia indicator. | |
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MedLine Citation:
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PMID: 22926387 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Glycated hemoglobin A1C reflects a mean glycemia over the preceding 3 months (erythrocyte life span). In diabetes management, target value is set below 6.5%, to reduce the risk of chronic complications. However, there are different conditions that lead to a shortened lifespan of erythrocytes, resulting in falsely low HbA1C value. Case presented involves a 72-year-old patient with history of diabetes and possible iatrogenic-induced autoimmune hemolytic anemia. Thus, HbA1C may be a screening test for hemolysis in non-diabetic patients with hemolytic anemia, but in diabetic population with hemolytic disease it is considered to be a very poor marker for both, overall glycemia and haemolysis. |
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Authors:
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Marica Jandrić Balen; Vesna Lukenda; Ivan Jandrić; Antonija Raguž; Sidbela Zukanović; Blaženka Miškić |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina Volume: 9 ISSN: 1840-0132 ISO Abbreviation: Med Glas (Zenica) Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-08-28 Completed Date: 2012-11-01 Revised Date: 2013-02-04 |
Medline Journal Info:
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Nlm Unique ID: 101250177 Medline TA: Med Glas (Zenica) Country: Bosnia and Hercegovina |
Other Details:
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Languages: eng Pagination: 406-8 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, General Hospital Dr. Josip Benčević, Slavonski Brod, Croatia. marica@jandric.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anemia, Hemolytic, Autoimmune / diagnosis*, etiology Biological Markers / blood Blood Glucose Diabetes Mellitus, Type 2 / blood*, complications Female Hemoglobin A, Glycosylated / analysis* Humans Hypoglycemic Agents / adverse effects, therapeutic use Metformin / adverse effects, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Blood Glucose; 0/Hemoglobin A, Glycosylated; 0/Hypoglycemic Agents; 657-24-9/Metformin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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