Document Detail

Hazards of ultra-marathon running in the Scottish Highlands: exercise-associated hyponatraemia.
MedLine Citation:
PMID:  19934147     Owner:  NLM     Status:  MEDLINE    
The case histories are presented of four athletes taking part in a 95-mile ultra-endurance foot race in Scotland who were hospitalised after developing exercise-associated hyponatraemia and rhabdomyolysis. Exercise-associated hyponatraemia is relatively uncommon in temperate climates. Risk factors disposing to this disorder are discussed. Exercise-associated hyponatraemia is thought to be due to overconsumption of hypotonic fluid with other associated pathophysiology including an inability to suppress fully antidiuretic hormone during exercise or to mobilise adequate sodium from osmotically inactive internal stores. Non-specific symptoms make this disorder difficult to diagnose on site without the assistance of serum sodium measurement, but any delay in treatment of patients with encephalopathy can prove fatal. Mainstays of treatment include fluid restriction, hypertonic saline, loop diuretics and mannitol.
J A Cuthill; C Ellis; A Inglis
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Emergency medicine journal : EMJ     Volume:  26     ISSN:  1472-0213     ISO Abbreviation:  Emerg Med J     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-25     Completed Date:  2010-01-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100963089     Medline TA:  Emerg Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  906-7     Citation Subset:  IM    
Intensive Care Unit, Glasgow Royal Infirmary, Glasgow, UK.
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MeSH Terms
Hyponatremia / etiology*,  physiopathology
Middle Aged
Physical Endurance / physiology
Rhabdomyolysis / etiology
Running / physiology*

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