| Hazards of epinephrine in transsphenoidal pituitary surgery. | |
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MedLine Citation:
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PMID: 11773822 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 79-year-old woman with no history of myocardial ischemia presented with symptoms of pituitary apoplexy for which an urgent transsphenoidal resection of the pituitary gland was undertaken. The nasal passages were prepared with topical application of epinephrine followed by injection of what was presumed to be 1% lidocaine containing 10 microg/ml(-1) of epinephrine. After only 1.5 mL of the solution had been injected, she developed a hypertensive crisis, which was immediately treated. Postoperatively, she developed a myocardial infarction. The risks associated with the use of vasopressors are reviewed and suggestions for their safe use are presented. |
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Authors:
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Y Rubuen Chelliah; Pirjo H Manninen |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of neurosurgical anesthesiology Volume: 14 ISSN: 0898-4921 ISO Abbreviation: J Neurosurg Anesthesiol Publication Date: 2002 Jan |
Date Detail:
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Created Date: 2002-01-04 Completed Date: 2002-01-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8910749 Medline TA: J Neurosurg Anesthesiol Country: United States |
Other Details:
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Languages: eng Pagination: 43-6 Citation Subset: IM |
Affiliation:
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Department of Anesthesia, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adjuvants, Anesthesia
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administration & dosage,
adverse effects Administration, Intranasal Aged Anesthetics, Local / administration & dosage Emergency Treatment Epinephrine / administration & dosage, adverse effects* Female Humans Hypertension / chemically induced* Hypophysectomy* Intraoperative Complications* Lidocaine / administration & dosage Myocardial Infarction / chemically induced, etiology Pituitary Apoplexy Postoperative Complications Sphenoid Bone / surgery* Vasoconstrictor Agents / administration & dosage, adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Adjuvants, Anesthesia; 0/Anesthetics, Local; 0/Vasoconstrictor Agents; 137-58-6/Lidocaine; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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