Document Detail

Hazards of assisted conception in women with severe medical disease.
MedLine Citation:
PMID:  11719719     Owner:  NLM     Status:  MEDLINE    
The issues relating to assisted reproduction in women with severe medical disease can be divided into the likely effect of pregnancy upon the medical condition, and how the medical condition may adversely affect pregnancy outcome. In addition, consideration of the hazards relating to the process of assisted conception, in particular the risk of ovarian hyperstimulation syndrome and multiple pregnancy, must be remembered. In some women, successful assisted reproduction may result in a life-threatening pregnancy. Clinicians advising women about assisted conception should be aware of the medical conditions that are absolute contra-indications to pregnancy. Some women with severe medical disease may have a significantly reduced life expectancy, in which case ethical issues regarding the future welfare of the child must be considered. Examples include sickle cell disease, cystic fibrosis and HIV. One of the biggest advantages of assisted reproduction for women with severe medical disorders is that the pregnancy is planned. Thus, there is an opportunity for the patient to be informed fully about any risks, both to herself and her fetus. This article reviews the general management of women with severe medical disorders who seek assisted reproduction and gives specific guidelines for the more common conditions.
A M Neill; C Nelson-Piercy
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Human fertility (Cambridge, England)     Volume:  4     ISSN:  1464-7273     ISO Abbreviation:  Hum Fertil (Camb)     Publication Date:  2001  
Date Detail:
Created Date:  2001-11-23     Completed Date:  2002-01-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100888143     Medline TA:  Hum Fertil (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  239-45     Citation Subset:  IM    
West Suffolk Hospital, Bury St Edmund's, Suffolk IP33 2QZ, UK.
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MeSH Terms
Child Welfare
Ovarian Hyperstimulation Syndrome
Pregnancy Complications
Pregnancy Complications, Infectious
Pregnancy, Multiple
Reproductive Techniques / contraindications*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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