Document Detail


Hazard Function Estimation with Cause-of-Death Data Missing at Random.
MedLine Citation:
PMID:  22267874     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Hazard function estimation is an important part of survival analysis. Interest often centers on estimating the hazard function associated with a particular cause of death. We propose three nonparametric kernel estimators for the hazard function, all of which are appropriate when death times are subject to random censorship and censoring indicators can be missing at random. Specifically, we present a regression surrogate estimator, an imputation estimator, and an inverse probability weighted estimator. All three estimators are uniformly strongly consistent and asymptotically normal. We derive asymptotic representations of the mean squared error and the mean integrated squared error for these estimators and we discuss a data-driven bandwidth selection method. A simulation study, conducted to assess finite sample behavior, demonstrates that the proposed hazard estimators perform relatively well. We illustrate our methods with an analysis of some vascular disease data.
Authors:
Qihua Wang; Gregg E Dinse; Chunling Liu
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Annals of the Institute of Statistical Mathematics     Volume:  64     ISSN:  1572-9052     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101509177     Medline TA:  Ann Inst Stat Math     Country:  -    
Other Details:
Languages:  ENG     Pagination:  415-438     Citation Subset:  -    
Affiliation:
Academy of Mathematics and Systems Science, Chinese Academy of Science Beijing 100080, China.
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Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
ZIA ES045007-13//NIEHS NIH HHS

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