Document Detail


Hay fever treatment with budesonide and beclomethasone dipropionate twice daily - a clinical comparison.
MedLine Citation:
PMID:  6364297     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fifty-two patients with seasonal allergic rhinitis were admitted to a randomized clinical comparison between budesonide (Rhinocort) and beclomethasone dipropionate (Becotide Nasal). All patients were sensitive to birch pollen, which was confirmed by a skin prick test. The drugs were administered intranasally 200 micrograms b.i.d. Symptoms were assessed over four weeks starting with a run-in period of one week. Daily pollen counts were recorded throughout the trial and showed a rather mild birch pollen season. The patients diary cards revealed a beneficial therapeutic effect of the two drugs. No statistically significant differences between the drugs were seen except with regard to sneezing symptoms, where the Rhinocort-treated patients showed less symptoms (p less than 0.05). Side effects were few and transient with both drugs.
Authors:
U Pipkorn
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Rhinology     Volume:  21     ISSN:  0300-0729     ISO Abbreviation:  Rhinology     Publication Date:  1983 Dec 
Date Detail:
Created Date:  1984-02-28     Completed Date:  1984-02-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0347242     Medline TA:  Rhinology     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  335-40     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Adolescent
Adult
Aerosols
Anti-Inflammatory Agents / administration & dosage*
Beclomethasone / administration & dosage*
Budesonide
Clinical Trials as Topic
Drug Administration Schedule
Female
Glucocorticoids
Humans
Male
Middle Aged
Nasal Provocation Tests
Pregnenediones / administration & dosage*
Random Allocation
Rhinitis, Allergic, Seasonal / drug therapy*
Chemical
Reg. No./Substance:
0/Aerosols; 0/Anti-Inflammatory Agents; 0/Glucocorticoids; 0/Pregnenediones; 4419-39-0/Beclomethasone; 51333-22-3/Budesonide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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