| Have We New Therapeutic Strategies in the Treatment of Renovascular Nephropathy? | |
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MedLine Citation:
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PMID: 22724464 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Renal artery stenosis (RAS) is a cause of hypertension and ischemic nephropathy. The incidence of this disorder is probably less than 1% in patients with mild hypertension, but rises to as high as 10 to 40% in patients with acute, severe or refractory hypertension. Significant RAS can be caused by atheromatous plaques, or due to fibromuscular dysplasia (FMD). Atherosclerotic lesions are present in almost 7% of adults older than 65 years and up to 50% of patients presenting with diffuse atherosclerotic disease. In contrast to atherosclerosis, FMD most often affects women under the age of 50 and typically involves the distal main renal artery or the intrarenal branches. The optimal treatment for RAS is not yet established. Based on recent trials, we reviewed the literature on pharmacological and endovascular treatment of atherosclerotic RAS and ischemic nephropathy. |
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Authors:
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Rosario Cianci; Alessandro Zuccalà; Gaetano Lucisano; Biagio Barbano; Paola Martina; Antonietta Gigante; Gianfranco Clemenzia; Giorgio Fuiano |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-22 |
Journal Detail:
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Title: Current vascular pharmacology Volume: - ISSN: 1875-6212 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-6-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101157208 Medline TA: Curr Vasc Pharmacol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Nephrology, �Sapienza� University of Rome, Viale del Policlinico 155, Rome, Italy. biagionet@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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