Document Detail

Hashimoto's encephalopathy presenting as an acute medical emergency.
MedLine Citation:
PMID:  15648714     Owner:  NLM     Status:  MEDLINE    
Three cases are described of a reversible encephalopathy, all presenting with marked neurological disturbance. In all three, the diagnosis was not clear at the time of presentation but eventually it was felt all of the cases were consistent with Hashimoto's encephalopathy. The diagnosis of Hashimoto's encephalopathy should be considered in any case of unexplained encephalopathy. Common features are high anti-thyroid peroxidase antibody titres, an abnormal EEG and an elevated CSF protein concentration. The encephalopathy is independent of thyroid hormonal status. Treatment with corticosteroids leads to a prompt resolution of symptoms and long-term low dose steroid therapy prevents further neurological recurrence.
A J Sommerfield; R Stimson; I W Campbell
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Scottish medical journal     Volume:  49     ISSN:  0036-9330     ISO Abbreviation:  Scott Med J     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2005-01-14     Completed Date:  2005-03-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2983335R     Medline TA:  Scott Med J     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  155-6     Citation Subset:  IM    
Department of Diabetes and Endocrinology, Victoria Hospital, Hayfield Road, Kirkcaldy, Scotland.
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MeSH Terms
Anti-Inflammatory Agents / therapeutic use
Brain Diseases, Metabolic / diagnosis,  drug therapy,  etiology*
Diagnosis, Differential
Headache / etiology
Seizures / etiology
Steroids / therapeutic use
Thyroiditis, Autoimmune / complications*
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Steroids

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