Document Detail

Hashimoto's encephalopathy in the elderly: relationship to cognitive impairment.
MedLine Citation:
PMID:  12230088     Owner:  NLM     Status:  MEDLINE    
Hashimoto's encephalopathy (HE) is a steroid-responsive encephalopathy associated with high titers of antithyroid antibodies. To date, 57 pediatric-, adult-, and elderly-onset cases have been described in the literature. The clinical picture is pleomorphic, and cognitive impairment is a frequently reported symptom. We report the case of a patient with slowly progressive cognitive impairment possibly caused by HE. The issue of the differential diagnosis with primary dementia is discussed. A review of cases of HE showing cognitive deterioration is also presented, and factors possibly related to characteristics of cognitive impairment and outcome after therapy are considered.
Samantha Galluzzi; Cristina Geroldi; Orazio Zanetti; Giovanni B Frisoni
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of geriatric psychiatry and neurology     Volume:  15     ISSN:  0891-9887     ISO Abbreviation:  J Geriatr Psychiatry Neurol     Publication Date:  2002  
Date Detail:
Created Date:  2002-09-16     Completed Date:  2003-02-13     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8805645     Medline TA:  J Geriatr Psychiatry Neurol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  175-9     Citation Subset:  IM    
Laboratory of Epidemiology and Neuroimaging, IRCCS San Giovanni di Dio-FBF, Brescia, Italy.
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MeSH Terms
Antibodies / blood,  immunology
Atrophy / pathology
Brain / pathology
Cerebrospinal Fluid Proteins
Cognition Disorders / diagnosis,  etiology*
Magnetic Resonance Imaging
Middle Aged
Neuropsychological Tests
Thyroid Gland / immunology
Thyroiditis, Autoimmune / complications*,  immunology,  pathology
Reg. No./Substance:
0/Antibodies; 0/Cerebrospinal Fluid Proteins

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