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Harmonizing national growth references for multi-centre surveys, drug monitoring, and international postmarketing surveillance.
MedLine Citation:
PMID:  21767311     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Hermanussen M, Aßmann C, Wöhling H, Zabransky M. Harmonizing national growth references for multi-centre surveys, drug monitoring, and international postmarketing surveillance. Aim:  National European growth references differ. We aimed to convert (harmonize) currently used charts into a single unified interchangeable LMS format for each European nation. Methods:  Nine currently used national European growth references from Belgium (2009), France (1979), Poland (2001), Sweden (2002), Switzerland (1989), the UK (1990), Italy (2006) and Germany (1979 and 1997) were harmonized and compared with the international WHO child growth standards and WHO growth reference data for 5-19 years. Results:  European growth charts can be harmonized. The approach appears useful as height and BMI is inappropriately represented by WHO references. European height references exhibit warping when plotted against the WHO reference. The French appear too short, the other Europeans too tall. Also the BMI is not appropriately represented by the WHO references. Conclusions:  Harmonizing references is a novel, convenient and cost-effective approach for converting historic and/or incomplete local or national growth reference charts into a unified interchangeable LMS format. Harmonizing facilitates producing growth references "on demand", for limited regional purposes, for ethnically, socio-economically or politically defined minorities, but also for matching geographically different groups of children and adolescents for international growth and registry studies.
Authors:
M Hermanussen; C Aßmann; H Wöhling; M Zabransky
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-18
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Acta Paediatrica © 2011 Foundation Acta Paediatrica.
Affiliation:
Aschauhof, Altenhof, Germany National Educational Panel Study, Otto-Friedrich-Universität Bamberg, Bamberg, Germany Sandoz Biopharmaceuticals, Hexal AG, Holzkirchen, Germany.
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