Document Detail

Harmonic scalpel in pharyngolaryngectomy with radical neck dissection.
MedLine Citation:
PMID:  19128668     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this study was to verify the efficacy and applicability of the Ultracision Harmonic Scalpel (Ethicon Endo-Surgery, Cincinnati, OH) in pharyngolaryngectomy with radical neck dissection.
DESIGN: This work evaluated the use of the Harmonic Scalpel in otolaryngology as a new and alternative method to overcome some complications of traditional surgery.
SETTING: The study was conducted with 20 patients in the ENT Department of the University of Genoa (Italy) between January 1, 2005, and December 31, 2006.
METHODS: A prospective, randomized study was undertaken on 20 pharyngolaryngectomies with radical neck dissection performed using a Harmonic Scalpel (10 patients) or traditional surgery (10 patients).
MAIN OUTCOME MEASURES: The evaluation included operation time, intraoperative blood loss, postoperative seroma formation, and pattern of wound healing.
RESULTS: In patients treated with Harmonic Scalpel, the mean operation time was significantly shorter, the blood loss was less, laryngeal and neck drainage on the first and second postoperative days was significantly smaller, and no postoperative complications were noted.
CONCLUSIONS: The use of the Harmonic Scalpel during pharyngolaryngectomy and radical neck dissection led to diminished bleeding, shorter operative time, less seroma formation, and better wound healing in the postoperative period.
Angelo Salami; Maurizio Bavazzano; Renzo Mora; Massimo Dellepiane
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale     Volume:  37     ISSN:  1916-0216     ISO Abbreviation:  J Otolaryngol Head Neck Surg     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2009-01-08     Completed Date:  2009-06-16     Revised Date:  2013-04-10    
Medline Journal Info:
Nlm Unique ID:  101479544     Medline TA:  J Otolaryngol Head Neck Surg     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  633-7     Citation Subset:  IM    
ENT Department, University of Genoa, Genoa, Italy.
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MeSH Terms
Blood Loss, Surgical / physiopathology
Carcinoma, Squamous Cell / pathology,  surgery
Combined Modality Therapy
Drainage / statistics & numerical data
Equipment Safety
Follow-Up Studies
Laryngeal Neoplasms / pathology,  surgery
Laryngectomy / instrumentation*,  methods
Laser Therapy
Length of Stay
Middle Aged
Neck Dissection / instrumentation*,  methods
Neoplasm Staging
Pain, Postoperative / physiopathology
Pharyngeal Neoplasms / pathology,  surgery
Pharyngectomy / instrumentation*,  methods
Prospective Studies
Reference Values
Regression Analysis
Risk Assessment
Sensitivity and Specificity
Surgical Instruments*
Time Factors
Treatment Outcome
Wound Healing / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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