Document Detail


Haptoglobin patterns in essential hypertension and associated conditions--increased risk for Hp 2-2.
MedLine Citation:
PMID:  3679234     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Blood samples from 257 hypertensive patients and 180 normotensive controls were analysed for their association with haptoglobin levels and phenotypes. Compared to controls, patients with Hp 2-2 phenotype showed a significantly increased risk for essential hypertension (p less than 0.001) and hypertension associated with ischaemic heart disease (p less than 0.05). There was a significant decrease in the mean levels of serum haptoglobins in hypertension as compared to controls, suggesting the possibility for intravascular haemolysis due to vascular damage leading to further complications.
Authors:
P Surya Prabha; T Padma; M Ramaswamy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human heredity     Volume:  37     ISSN:  0001-5652     ISO Abbreviation:  Hum. Hered.     Publication Date:  1987  
Date Detail:
Created Date:  1988-01-14     Completed Date:  1988-01-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0200525     Medline TA:  Hum Hered     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  345-8     Citation Subset:  IM    
Affiliation:
Department of Genetics, Osmania University, Hyderabad, India.
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MeSH Terms
Descriptor/Qualifier:
Diabetes Complications
Diabetes Mellitus / blood
Haptoglobins / metabolism*
Humans
Hypertension / blood*
Myocardial Infarction / blood,  complications
Phenotype
Risk
Chemical
Reg. No./Substance:
0/Haptoglobins

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