| Haptoglobin: an immunoregulatory role in tuberculosis? | |
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MedLine Citation:
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PMID: 3984037 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A significant correlation was found between levels of haptoglobin in sera from Indonesian patients with tuberculosis and the extent to which these sera suppressed mitogen-driven activation of normal lymphocytes in vitro. As in a previous study we showed that there was an inverse relationship between haptoglobin levels and the circulating lymphocyte count in the same group of patients, it is now suggested that this protein has an immunoregulatory role in tuberculosis. Similar observations have been made by other workers on patients with cancer. There was no difference in the distribution of the 3 allotypes of haptoglobin in patients and healthy subjects nor was there any association between such allotypes and the lymphocyte count, the dermal reactivity to tuberculin or the degree of suppression. |
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Authors:
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J M Grange; T Kardjito; J S Beck; O Ebeid; W Köhler; O Prokop |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Tubercle Volume: 66 ISSN: 0041-3879 ISO Abbreviation: Tubercle Publication Date: 1985 Mar |
Date Detail:
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Created Date: 1985-05-09 Completed Date: 1985-05-09 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1273730 Medline TA: Tubercle Country: SCOTLAND |
Other Details:
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Languages: eng Pagination: 41-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Agglutination Tests Complement System Proteins / analysis Electrophoresis Haptoglobins / analysis, immunology* Humans Immunoglobulins / analysis Lymphocyte Activation Skin Tests Tuberculosis, Pulmonary / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Haptoglobins; 0/Immunoglobulins; 9007-36-7/Complement System Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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