Document Detail


Haploid embryonic stem cells and the dominance of recessive traits.
MedLine Citation:
PMID:  22136917     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Diploidy, though essential for normal development, is a foil to geneticists. Two recent studies (Elling et al., 2011, this issue of Cell Stem Cell; Leeb and Wutz, 2011, Nature), report the isolation of haploid pluripotent mouse ESCs, thus enabling efficient functional screening for genes involved in diverse cellular and developmental processes.
Authors:
John Schimenti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell stem cell     Volume:  9     ISSN:  1875-9777     ISO Abbreviation:  Cell Stem Cell     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101311472     Medline TA:  Cell Stem Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  488-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Center for Vertebrate Genomics, Cornell University, Ithaca, NY 14850, USA.
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