Document Detail

Hantavirus pulmonary syndrome in Texas: 1993-2006.
MedLine Citation:
PMID:  19077779     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Hantavirus pulmonary syndrome (HPS) is a rare cardiopulmonary disease that was first described after a 1993 epidemic in the southwestern United States. This study reviewed all cases reported in Texas to date.
METHODS: We reviewed case report forms submitted to the Texas Department of State Health Services and medical records (when available) to determine demographic and clinical features of Texas HPS cases.
CONCLUSIONS: Middle-aged adults were more commonly affected. Respiratory symptoms were often accompanied by fever, gastrointestinal symptoms, and headache. Hypoxemia was observed in all cases. Common laboratory features included thrombocytopenia (92% of patients), elevated creatinine (61% of patients), increased polymorphonuclear leukocyte band forms (52% of patients), and hematocrit more than 55% (32% of patients). Most cases were associated with seeing rodents or rodent excreta at home. HPS was frequently misdiagnosed on initial presentation. Mortality was over 46%, higher for infection with the Sin Nombre virus (50%) than with the Bayou virus (0%). In Texas, the distribution of HPS is mainly along the coast and in west Texas.
Megan N Rivers; James L Alexander; Rodney E Rohde; J Rush Pierce
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  102     ISSN:  1541-8243     ISO Abbreviation:  South. Med. J.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-06     Completed Date:  2009-02-04     Revised Date:  2011-10-12    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  36-41     Citation Subset:  AIM; IM    
Division of Preventive Medicine, Department of Internal Medicine, Texas Tech University Health Sciences Center, Amarillo, TX 79106, USA.
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MeSH Terms
Biological Markers / blood
Disease Reservoirs
Gastrointestinal Diseases / virology
Hantavirus Pulmonary Syndrome / diagnosis,  epidemiology*,  mortality,  transmission
Middle Aged
Residence Characteristics
Retrospective Studies
Risk Factors
Texas / epidemiology
Reg. No./Substance:
0/Biological Markers
Comment In:
South Med J. 2011 Jul;104(7):540-1; author reply 541   [PMID:  21886056 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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