Document Detail

Handgrip exercise: From an alternative test to a promising associated cardiovascular technique of noninvasive diagnosis of coronary artery disease.
MedLine Citation:
PMID:  19473716     Owner:  NLM     Status:  In-Data-Review    
Isometric handgrip exercise (HG) was proposed as one of alternative substitute test for the more conventional exercise stress testing but the value of this test alone is limited by a relatively low sensitivity for detecting the presence of coronary artery disease (CAD).On the contrary, the combination of dipyridamole-HG stress with positron imaging of myocardial perfusion became a powerful diagnostic tool suitable for routine clinical use. Stress echocardiography with dobutamine or vasodilators is today the best (most cost-effective and risk-effective) possible imaging choice to achieve the still elusive target of sustainable cardiac imaging in the field of noninvasive diagnosis of CAD. Adjunctive sustained submaximal HG to peak of dobutamine stress echocardiography (DSE) without atropine showed a potential improvement of its ability to detect physiologically significant stenoses. Recently, it has also been demonstrated the safe, feasibility and efficacy of use of HG exercise with DSE. Adjunctive application of HG associated with dobutamine stress echocardiography is a promising technique. Large studies need to be done to confirm this hypothesis but the journey of this old-new test could be longer than expected.
Salvatore Patanè; Annalisa Lamari; Filippo Marte; Mauro Sturiale; Giuseppe Dattilo
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Publication Detail:
Type:  Journal Article     Date:  2009-05-26
Journal Detail:
Title:  International journal of cardiology     Volume:  148     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  347-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.
Cardiologia Nuovo Presidio Ospedaliero Cutroni Zodda-Barcellona P.d.G (Me) AUSL5 Messina, Italy.
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