Document Detail

Handedness in schizophrenia: a quantitative review of evidence.
MedLine Citation:
PMID:  15877707     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The prevalence of various anomalous handedness subtypes in schizophrenia patients remains ambiguous. Although current literature favours the notion that the shift in lateral preferences seen is because of an increase of mixed-handedness, several studies suggest that exclusive left handedness is more prevalent than in the general population. METHOD: Over 40 studies with reported prevalence data on various handedness subtypes in a schizophrenia population were evaluated by meta-analysis. Combined odds ratios for the three common handedness subtypes (left, mixed, and right) were separately calculated. RESULTS: Each of the three atypical hand dominance patterns were significantly greater in schizophrenia patients than in control subjects, showing that the leftward shift in handedness distribution is not entirely because of an increase in mixed-handedness alone. CONCLUSION: An increase of exclusive left-handedness is at variance with the prevailing assertion that the handedness shift in schizophrenia patients is because of a diffuse and bilateral hemispheric insult.
M Dragovic; G Hammond
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta psychiatrica Scandinavica     Volume:  111     ISSN:  0001-690X     ISO Abbreviation:  Acta Psychiatr Scand     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-09     Completed Date:  2005-10-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370364     Medline TA:  Acta Psychiatr Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  410-9     Citation Subset:  IM    
Centre for Clinical Research in Neuropsychiatry, Claremont, WA, Australia.
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MeSH Terms
Functional Laterality / physiology*
Psychiatric Status Rating Scales
Schizophrenia / epidemiology*,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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