Document Detail


Hand and upper limb anomalies in poland syndrome: a new proposal of classification.
MedLine Citation:
PMID:  22955538     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: : The Poland anomaly (PA) comprises unilateral absence or hypoplasia of the pectoralis major muscle and a variable degree of ipsilateral hand and upper limb anomalies. Various hand and upper limb anomalies classifications in PA have been previously published. In this work, a new classification of hand and upper limb anomalies in PA is proposed, on the basis of the clinical and instrumental evaluation of 175 patients.
METHODS: : The patients have been followed by a multidisciplinary approach, consisting in orthopaedic, surgical, and genetic evaluation and chest, upper limb, and ultrasound examination of major and minor pectoralis muscles, heart, and kidney.
RESULTS: : Hand and upper limb anomalies were classified in 8 groups on the basis of the clinical degree of severity and on the basis of the presence of coexisting associated anomalies. Data regarding the sex and laterality, previously reported in the medical literature, were confirmed by our analysis. Etiopathogenetic mechanisms leading to the anomaly are discussed.
CONCLUSIONS: : The proposed classification is derived from the observation of the widest group of patients described in the medical literature. Our proposal could help in the management of patients affected by Poland syndrome and in understanding etiological and pathologic aspects of the disease.
LEVEL OF EVIDENCE: : IV.
Authors:
Nunzio Catena; Maria T Divizia; Maria G Calevo; Anwar Baban; Michele Torre; Roberto Ravazzolo; Margherita Lerone; Filippo M Sénès
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric orthopedics     Volume:  32     ISSN:  1539-2570     ISO Abbreviation:  J Pediatr Orthop     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8109053     Medline TA:  J Pediatr Orthop     Country:  United States    
Other Details:
Languages:  eng     Pagination:  727-31     Citation Subset:  IM    
Affiliation:
*Microsurgery and Hand Surgery Unit-Orthopaedics and Traumatology Department †Molecular Genetics Unit ‡Epidemiology and Biostatistics Section, Scientific Direction §Surgery Unit, G. Gaslini Institute, Genoa, Italy.
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