Document Detail

Hamster embryo cells transformed by herpes simplex virus: reactions with adeno-associated satellite virus (AAV) and its adenovirus helpers.
MedLine Citation:
PMID:  210924     Owner:  NLM     Status:  MEDLINE    
We have studied the reactions of hamster embryo cells transformed by ultraviolet-inactivated herpes simplex type 2 (333-8-9 T cells) to infections with adeno-associated satellite virus (AAV) and its adenovirus helpers. Resident HSV structural antigens were not detectable in early or late passage of 333-8-9 T cells. AAV structural antigens were not detected in these cells unless the cells were coinfected with a helper adenovirus. In early passage 333-8-9 T cells were permissive to infections with simian adenovirus SV15 whereas normal hamster cell line LSH was nonpermissive. In some late passages of 333-8-9 T cells infections with SV15 adenovirus led to the production of viruslike particles whose morphology was identical with reoviruses.
H D Mayor; L E Jordan; C Gorman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cancer biochemistry biophysics     Volume:  2     ISSN:  0305-7232     ISO Abbreviation:  Cancer Biochem. Biophys.     Publication Date:  1977  
Date Detail:
Created Date:  1978-11-18     Completed Date:  1978-11-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7506524     Medline TA:  Cancer Biochem Biophys     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  25-31     Citation Subset:  IM    
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MeSH Terms
Adenoviruses, Human
Adenoviruses, Simian
Antigens, Viral
Cell Transformation, Neoplastic*
Dependovirus* / immunology
Genes, Viral
Helper Viruses
Inclusion Bodies, Viral
Microscopy, Electron
Simplexvirus* / genetics,  immunology
Reg. No./Substance:
0/Antigens, Viral

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