Document Detail

Halothane-associated granulomatous hepatitis.
MedLine Citation:
PMID:  6671485     Owner:  NLM     Status:  MEDLINE    
We present a case of halothane-associated-hepatitis in a 34-year-old woman. She received halothane anesthesia twice within a 6-day interval, 2 weeks prior to the onset of symptoms. Liver histology was nonspecific, and unusual in showing not only lobular hepatitis but also granulomatous changes. Since the clinical picture and the laboratory values were more and the liver histology less in keeping with the diagnosis, we emphasize that the former two parameters should play a vital role in establishing or discarding the diagnosis of halothane-induced hepatitis.
I A Shah; H Brandt
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Digestion     Volume:  28     ISSN:  0012-2823     ISO Abbreviation:  Digestion     Publication Date:  1983  
Date Detail:
Created Date:  1984-05-10     Completed Date:  1984-05-10     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  245-9     Citation Subset:  IM    
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MeSH Terms
Biopsy, Needle
Drug-Induced Liver Injury / etiology,  pathology*
Granuloma / etiology,  pathology*
Halothane / adverse effects*
Liver / pathology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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